SCHEMBL29622774

SCHEMBL29622774

CCS(=O)(=O)c1ccc(OC)c(C(N)=O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
DRD2 P14416 2/20 0.50
DRD3 P35462 2/20 0.50
HTR2B P41595 2/20 0.50
KCNH2 Q12809 2/20 0.50
ADRA2B P18089 1/20 0.50
ADRA2C P18825 1/20 0.50
SLC6A4 P31645 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
MAPK1 P28482 3/20 0.47
LMNA P02545 3/20 0.47
RAB9A P51151 1/20 0.47
FLT1 P17948 1/20 0.47
FLT4 P35916 1/20 0.47
KDR P35968 1/20 0.47
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348770 1.00 GAA (0.51) GAAMEN1KMT2ADRD2DRD3
SCHEMBL10744283 0.88 POLB (0.46) GAADRD2DRD3HTR2BKCNH2
SCHEMBL8544664 0.86 MAPK1 (0.56) GAADRD2DRD3HTR2BKCNH2
SCHEMBL21054952 0.85 GAA (0.56) GAAMEN1KMT2ADRD2DRD3
SCHEMBL10744279 0.84 GAA (0.51) GAAMEN1KMT2ADRD2DRD3
SCHEMBL27631394 0.84 GAA (0.55) GAAMEN1KMT2ADRD2DRD3
SCHEMBL10723820 0.84 DRD2 (0.50) GAADRD2DRD3HTR2BKCNH2
SCHEMBL31038303 0.84 CA2 (0.52) GAAMEN1KMT2AMAPK1ALDH1A1
SCHEMBL30219287 0.84 SMN1; SMN2 (0.57) GAAMEN1KMT2ADRD2DRD3
SCHEMBL29598834 0.84 GAA (0.65) GAAMEN1KMT2ADRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436927-B Amisulpride derivative, homogeneous enzyme immunoassay reagent and preparation method 合肥爱索特克医学检验实验室有限公司 2024-07-19 CN disclosed
CN-113735755-B Preparation method of amisulpride 深圳市新浩瑞医药科技有限公司 2024-05-31 CN disclosed
CN-116836093-A 4-amino-5-alkylsulfinyl-2-methoxybenzoic acid compound and preparation method and application thereof 江苏恩华药业股份有限公司 2023-10-03 CN disclosed
CN-116621752-A Preparation method of amisulpride impurity B 广州隽沐生物科技股份有限公司 2023-08-22 CN disclosed
CN-115300471-B Orally disintegrating amisulpride tablet and preparation method thereof 则正(济南)生物科技有限公司 2022-12-23 CN disclosed
CN-115300471-A Orally disintegrating amisulpride tablet and preparation method thereof 则正(济南)生物科技有限公司 2022-11-08 CN disclosed
US-20220323409-A1 MODIFIED RELEASE FORMULATIONS AND USES THEREOF SUNOVION PHARMACEUTICALS INC. 2022-10-13 US disclosed
CN-114507174-A Synthesis method of amisulpride impurity H 浙江华海药业股份有限公司 2022-05-17 CN disclosed
CN-114436927-A Amisulpride derivative, homogeneous enzyme immunoassay reagent and preparation method 安徽爱索特克医学检验实验室有限公司 2022-05-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220323409-A1 MODIFIED RELEASE FORMULATIONS AND USES THEREOF RYR2, ABCG2, ATP2A3 GAA 476/4885MEN1 2905/4885KMT2A 4777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.