Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.60 |
| ▸ | NNMT | P40261 | 2/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1221922 | 0.87 | MAPT (0.63) | CXCR2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL23488401 | 0.85 | SIRT2 (0.53) | PARP10OPRK1OPRM1OPRD1NNMT | |
| SCHEMBL1091737 | 0.84 | MAOB (0.62) | PARP10CXCR2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL20830743 | 0.83 | CHRNB2 (0.61) | CXCR2SLC6A2SLC6A3CHRNB2CHRNA7 | |
| SCHEMBL27888270 | 0.82 | CXCR2 (0.52) | PARP10OPRK1OPRM1OPRD1CXCR2 | |
| SCHEMBL3506490 | 0.82 | CXCR2 (0.49) | PARP10OPRK1OPRM1OPRD1NNMT | |
| SCHEMBL3506489 | 0.82 | SPHK2 (0.62) | PARP10OPRK1OPRM1OPRD1CXCR2 | |
| SCHEMBL28703922 | 0.82 | CXCR2 (0.64) | CXCR2CHRNB2CHRNA7CHRNA4 | |
| Nitrous Acid SCHEMBL27888273 | 0.82 | MAPT (0.56) | CXCR2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL246555 | 0.82 | GABRA5 (0.60) | CXCR2CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | PARP10 1135/4885OPRK1 3313/4885OPRM1 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.