Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 20/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21792175 | 0.83 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL23488344 | 0.80 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21792146 | 0.80 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL23488082 | 0.79 | NOTUM (0.82) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21792339 | 0.77 | NOTUM (0.77) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL23488083 | 0.77 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21777034 | 0.77 | NOTUM (1.00) | NOTUM | |
| SCHEMBL21776980 | 0.76 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21792139 | 0.75 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL21776884 | 0.71 | NOTUM (1.00) | NOTUMCYP1A2CYP2C9CHRNB2CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171475-A1 | COMPOUNDS | GOT2, GOT1, OAT | NOTUM 5/4885CYP1A2 1415/4885CYP2C9 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.