Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23488116 | 0.86 | ADRB2 (0.41) | NT5EADRB2ADRB1ADRB3PTPN1 | |
| SCHEMBL15953011 | 0.79 | ALDH1A1 (0.47) | ALDH1A1NT5EPTPN1CYP3A4 | |
| SCHEMBL23488672 | 0.78 | ALDH1A1 (0.54) | ALDH1A1ADRB2ADRB1ADRB3HIF1A | |
| SCHEMBL23488461 | 0.78 | ALDH1A1 (0.54) | ALDH1A1ADRB2ADRB1ADRB3HIF1A | |
| SCHEMBL22490847 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ADRB2ADRB1ADRB3HIF1A | |
| SCHEMBL22490882 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ADRB2ADRB1ADRB3HIF1A | |
| SCHEMBL22490892 | 0.75 | ADRB2 (0.39) | ALDH1A1NT5EADRB2ADRB1ADRB3 | |
| SCHEMBL6758122 | 0.74 | SSTR1 (0.42) | ALDH1A1NT5EPTPN1PTPN2CYP3A4 | |
| SCHEMBL6806216 | 0.73 | ALDH1A1 (0.38) | ALDH1A1CYP3A4 | |
| SCHEMBL8815770 | 0.73 | ALDH1A1 (0.56) | ALDH1A1ADRB2ADRB1ADRB3HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | ALDH1A1 1627/4885NT5E 2310/4885ADRB2 2675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.