SCHEMBL23488579

SCHEMBL23488579

COc1c(Cl)c(OCc2ccccc2)c(Cl)c(C)c1C(=O)OC[C@H]1O[C@H](OC)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.40
SLC5A1 P13866 2/20 0.38
SLC5A2 P31639 2/20 0.38
SLC6A2 P23975 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
PDE4D Q08499 1/20 0.35
SYNJ2 O15056 3/20 0.35
TYMP P19971 1/20 0.35
XDH P47989 1/20 0.35
KCNA3 P22001 1/20 0.35
SLC22A1 O15245 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488282 1.00 LGALS8 (0.40) LGALS8SLC5A1SLC5A2SLC6A2TDP1
SCHEMBL23488516 1.00 LGALS8 (0.40) LGALS8SLC5A1SLC5A2SLC6A2TDP1
SCHEMBL22490880 0.89 TNF (0.37) LGALS8PDE4DKCNA3
SCHEMBL23488306 0.85 TDP1 (0.41) LGALS8SLC5A1SLC5A2SLC6A2TDP1
SCHEMBL23488170 0.84 LGALS8 (0.47) LGALS8SLC5A1SLC5A2SLC6A2KCNA3
SCHEMBL23488518 0.84 LGALS8 (0.47) LGALS8SLC5A1SLC5A2SLC6A2KCNA3
SCHEMBL23488522 0.84 LGALS8 (0.47) LGALS8SLC5A1SLC5A2SLC6A2KCNA3
SCHEMBL23488529 0.84 LGALS8 (0.40) LGALS8SLC5A1SLC5A2SLC6A2TDP1
SCHEMBL23488645 0.84 LGALS8 (0.40) LGALS8SLC5A1SLC5A2TDP1PDE4D
SCHEMBL23488158 0.82 LGALS8 (0.55) LGALS8SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS8 61/4885SLC5A1 9/4885SLC5A2 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.