SCHEMBL23488707

SCHEMBL23488707

COc1cc(C(=O)O[C@H]2[C@@H](OC)O[C@H](CO)[C@H](O)[C@@H]2O)cc(Cl)c1OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.47
KDM4E B2RXH2 1/20 0.44
LGALS3 P17931 5/20 0.43
LGALS9 O00182 2/20 0.43
LGALS1 P09382 2/20 0.43
LGALS7; LGALS7B P47929 2/20 0.43
LGALS4 P56470 2/20 0.41
EPHX2 P34913 1/20 0.41
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23488610 1.00 LGALS8 (0.47) LGALS8KDM4ELGALS3LGALS9LGALS1
SCHEMBL23488701 0.94 LGALS8 (0.50) LGALS8KDM4ELGALS3LGALS9LGALS1
SCHEMBL23488294 0.93 LGALS8 (0.55) LGALS8KDM4ELGALS3LGALS9LGALS1
SCHEMBL23488176 0.92 SLC5A2 (0.44) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488633 0.92 LGALS3 (0.46) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488428 0.92 LGALS3 (0.42) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488445 0.91 LGALS3 (0.40) LGALS8KDM4ELGALS3LGALS9LGALS1
SCHEMBL23488734 0.90 LGALS3 (0.40) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL24137795 0.88 LGALS8 (0.45) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B
SCHEMBL23488425 0.88 EPHX2 (0.45) LGALS8LGALS3LGALS9LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN SANOFI (FR) 2021-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170033-A1 NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN GPR119, SLC2A8, SLC2A4 LGALS8 61/4885KDM4E 4293/4885LGALS3 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.