Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035659 | 0.91 | TSHR (0.55) | TSHRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL11375136 | 0.84 | LMNA (0.77) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL10301412 | 0.84 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL13113118 | 0.81 | LMNA (0.67) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL6311599 | 0.81 | TSHR (0.61) | LMNACYP1A2TSHRCYP2C9CYP2C19 | |
| SCHEMBL10301414 | 0.81 | NPC1 (0.64) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL10301408 | 0.81 | LMNA (0.63) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL16270508 | 0.81 | CYP1A2 (0.56) | LMNACYP1A2CYP3A4MAOATSHR | |
| SCHEMBL4268692 | 0.81 | MAPT (0.56) | LMNACYP3A4TSHRCYP2C9CYP2C19 | |
| SCHEMBL3438972 | 0.80 | LMNA (0.60) | LMNACYP1A2CYP3A4MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-8007526-B2 | Difunctionalized aromatic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-8007526-B2 | Difunctionalized aromatic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-8007526-B2 | Difunctionalized aromatic compounds and polymers therefrom | BEZWADA BIOMEDICAL, LLC (US) | 2011-08-30 | — | — | US | disclosed |
| US-20070129787-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070129787-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070129787-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | BEZWADA BIOMEDICAL, LLC (US) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313057-A1 | DIFUNCTIONALIZED AROMATIC COMPOUNDS AND POLYMERS THEREFROM | AHR, OGFR, OPRM1 | LMNA 3132/4885CYP1A2 41/4885CYP3A4 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.