Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23462475 | 1.00 | LMNA (0.40) | LMNAEPHX1NPBWR1MCHR1MEN1 | |
| SCHEMBL23490342 | 0.93 | DRD2 (0.38) | LMNANPBWR1MCHR1 | |
| SCHEMBL23489791 | 0.89 | EPHX1 (0.37) | LMNAEPHX1POLBALDH1A1 | |
| SCHEMBL23489800 | 0.89 | EPHX1 (0.37) | LMNAEPHX1POLBALDH1A1 | |
| SCHEMBL23462340 | 0.89 | JAK3 (0.35) | LMNANPBWR1MCHR1 | |
| SCHEMBL23490340 | 0.86 | SMYD3 (0.34) | LMNAEPHX1POLBALDH1A1 | |
| SCHEMBL23462554 | 0.85 | L3MBTL1 (0.31) | LMNAPOLBALDH1A1 | |
| SCHEMBL23462555 | 0.82 | L3MBTL1 (0.31) | — | |
| SCHEMBL23462522 | 0.81 | L3MBTL1 (0.30) | LMNAPOLBALDH1A1 | |
| SCHEMBL23490329 | 0.79 | POLB (0.42) | EPHX1NPBWR1MCHR1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113625-A1 | COMPOUNDS AND METHODS FOR CD73 MODULATION AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2021-06-10 | — | — | WO | disclosed |