Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23491962 | 0.85 | FOLH1 (0.46) | RAB9AKMT2A | |
| SCHEMBL23493014 | 0.83 | SLC7A5 (0.52) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL23491965 | 0.78 | BCL9 (0.40) | ALDH1A1HTR1AMAPK1L3MBTL1 | |
| SCHEMBL23491248 | 0.76 | CYP1A2 (0.39) | RAB9AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23491900 | 0.75 | CYP1A2 (0.52) | RAB9ASMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL23493133 | 0.73 | GABRP (0.40) | ALDH1A1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL19421520 | 0.72 | KMT2A (0.59) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8050669 | 0.72 | ALDH1A1 (0.53) | RAB9AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10224082 | 0.71 | HPGD (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL13533212 | 0.71 | HPGD (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113682-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |