Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23491962 | 0.91 | FOLH1 (0.46) | RAB9AFOLH1SLC6A2SLC6A3KMT2A | |
| SCHEMBL23491940 | 0.83 | RAB9A (0.44) | TSHRRAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23491965 | 0.81 | BCL9 (0.40) | ALDH1A1 | |
| SCHEMBL23491248 | 0.78 | CYP1A2 (0.39) | RAB9AMAPTALDH1A1KMT2AGLA | |
| SCHEMBL23493133 | 0.78 | GABRP (0.40) | ALDH1A1KMT2A | |
| SCHEMBL18465773 | 0.78 | MAPT (0.50) | RAB9AMAPTSMN1; SMN2ALDH1A1SLC6A2 | |
| SCHEMBL23491900 | 0.78 | CYP1A2 (0.52) | RAB9AMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2790847 | 0.77 | MAPT (0.56) | TSHRRAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6669062 | 0.76 | RAB9A (0.75) | SLC7A5TSHRRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8050669 | 0.76 | ALDH1A1 (0.53) | RAB9AMAPTALDH1A1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021113682-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |