Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 7/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.52 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25586296 | 0.79 | DNPH1 (0.51) | P2RY6 | |
| SCHEMBL22863025 | 0.76 | P2RY2 (0.56) | P2RY6P2RY14 | |
| SCHEMBL18512787 | 0.75 | P2RY2 (0.45) | P2RY6P2RY14 | |
| SCHEMBL21742396 | 0.74 | P2RY6 (0.83) | NT5EP2RY6P2RY14 | |
| SCHEMBL22607099 | 0.72 | P2RY2 (0.60) | P2RY6P2RY14 | |
| SCHEMBL18512916 | 0.70 | LMNA (0.41) | P2RY6 | |
| SCHEMBL21742490 | 0.69 | P2RY6 (1.00) | NT5EP2RY6P2RY14 | |
| SCHEMBL23493260 | 0.69 | P2RY6 (1.00) | NT5EP2RY6P2RY14 | |
| SCHEMBL23921555 | 0.68 | P2RY2 (0.38) | P2RY6 | |
| SCHEMBL25719815 | 0.68 | P2RY2 (0.48) | P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210169911-A1 | PURINE AND PYRIMIDINE NUCLEOTIDES AS ECTO-5'-NUCLEOTIDASE INHIBITORS | THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210169911-A1 | PURINE AND PYRIMIDINE NUCLEOTIDES AS ECTO-5'-NUCLEOTIDASE INHIBITORS | NUDT1, NTPCR, NT5C2 | NT5E 11/4885P2RY6 70/4885P2RY14 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.