SCHEMBL23494232

SCHEMBL23494232

C=CC(=O)Oc1c(CC)ccc2c1Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.42
NPC1 O15118 3/20 0.42
THRB P10828 3/20 0.39
THRA P10827 1/20 0.39
PNMT P11086 1/20 0.38
MAPT P10636 3/20 0.36
HTR2B P41595 3/20 0.34
KDM4E B2RXH2 3/20 0.34
HTR7 P34969 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045273 0.85 RAB9A (0.41) RAB9ANPC1THRBTHRAPNMT
SCHEMBL23494185 0.82 NPC1 (0.45) RAB9ANPC1PNMTMAPTHTR2B
SCHEMBL25297197 0.81 RAB9A (0.38) RAB9ANPC1THRBTHRAPNMT
SCHEMBL12701591 0.78 RAB9A (0.42) RAB9ANPC1PNMTMAPTHTR2B
SCHEMBL27716115 0.77 RAB9A (0.38) RAB9ANPC1THRBTHRAPNMT
SCHEMBL29117658 0.76 NPC1 (0.36) RAB9ANPC1PNMTMAPTHTR2B
SCHEMBL28167127 0.76 GABRP (0.39) RAB9ANPC1THRBTHRAMAPT
SCHEMBL31059002 0.76 RAB9A (0.35) RAB9ANPC1THRBTHRAPNMT
SCHEMBL1331344 0.76 RAB9A (0.44) RAB9ANPC1THRBTHRAPNMT
SCHEMBL27716086 0.75 THRB (0.38) RAB9ANPC1THRBTHRAPNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP claimed
US-11365273-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-21 US claimed
EP-3839018-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP claimed
CN-112980549-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN claimed
US-20210179760-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US claimed
US-20210179965-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US claimed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP disclosed
US-11365273-B2 High viscosity index comb polymer viscosity modifiers and methods of modifying lubricant viscosity using same INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-21 US disclosed
EP-3839018-A1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME Infineum International Limited (GB) 2021-06-23 EP disclosed
CN-112980549-A High viscosity index comb polymer viscosity modifiers and methods of using the same to modify lubricant viscosity 英菲诺姆国际有限公司 2021-06-18 CN disclosed
US-20210179760-A1 High Viscosity Index Comb Polymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed
US-20210179965-A1 High Viscosity Index Comb Copolymer Viscosity Modifiers and Methods of Modifying Lubricant Viscosity Using Same INFINEUM INTERNATIONAL LIMITED (GB) 2021-06-17 US disclosed