Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234985 | 1.00 | NAMPT (0.41) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL7639531 | 0.92 | NAMPT (0.44) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL9042892 | 0.89 | CHRNB2 (0.38) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL9042886 | 0.89 | CHRNB2 (0.38) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL7644677 | 0.89 | FAAH (0.43) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL7644681 | 0.89 | FAAH (0.43) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL8867156 | 0.86 | ALDH1A1 (0.42) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL9026957 | 0.86 | FAAH (0.44) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL13240165 | 0.86 | ALDH1A1 (0.39) | NAMPTCYP2C9FAAHALDH1A1KDM4E | |
| SCHEMBL8867144 | 0.86 | ALDH1A1 (0.42) | NAMPTCYP2C9FAAHALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873325-B1 | PROCESS FOR PRODUCING GUANIDINE DERIVATIVES, INTERMEDIATES THEREFOR AND THEIR PRODUCTION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | claimed |
| CN-1060615-C | Guanidine derivatives, their production and insecticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-01-17 | — | — | CN | claimed |
| US-6140350-A | APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | claimed |
| CN-1044071-C | Insecticidal agents | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1999-07-14 | — | — | CN | claimed |
| EP-0873325-A1 | PROCESS FOR PRODUCING GUANIDINE DERIVATIVES, INTERMEDIATES THEREFOR AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1998-10-28 | — | — | EP | claimed |
| CN-1188475-A | Guanidine derivatives, intermediates thereof and process for preparing products thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-22 | — | — | CN | claimed |
| US-RE35811-E | PESTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-26 | — | — | US | claimed |
| WO-1997000867-A1 | PROCESS FOR PRODUCING GUANIDINE DERIVATIVES, INTERMEDIATES THEREFOR AND THEIR PRODUCTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-09 | — | — | WO | claimed |
| EP-0375907-B1 | Insecticidally active nitro compounds | BAYER AGROCHEM KK (JP) | 1996-01-03 | — | — | EP | claimed |
| CN-1026981-C | Process for the preparation of guanidine derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-12-14 | — | — | CN | claimed |
| CN-1077843-A | GUANIDINE DERIVATIVES, THEIR PRODUCTION AND INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-11-03 | — | — | CN | claimed |
| US-5166164-A | Nontoxic to mammals, fish, and crustaceans; nonphytotoxic | AGRO-KANESHO CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| EP-0493369-A1 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1992-07-01 | — | — | EP | claimed |
| CN-1061598-A | Hydrazine class compound or its salt, its preparation method and contain the sterilant of this compounds | ISHIHRA SANGYO KAISHA LTD (JP) | 1992-06-03 | — | — | CN | claimed |
| EP-0483647-A1 | Hydrazine compounds or their salts, processes for producing them and pesticides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-05-06 | — | — | EP | claimed |
| US-5051434-A | Pyridyl, thiazolyl, thiadiazolyl, pyrimidinyl or isooxazolyl groups | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-09-24 | — | — | US | claimed |
| CN-1045333-A | Insecticide | NIHON TOKUSHU NOYAKU SEIZO KK (JP) | 1990-09-19 | — | — | CN | claimed |
| CN-1045261-A | Guanidine derivatives, their production and pesticides | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-09-12 | — | — | CN | claimed |
| EP-0376279-A2 | Guanidine derivatives, their production and insecticides | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | claimed |
| EP-0375907-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-07-04 | — | — | EP | claimed |