Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.31 |
| ▸ | MTOR | P42345 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776740 | 0.81 | KCNH2 (0.33) | DHFRDCPSKCNH2PIK3CAPIK3R1 | |
| SCHEMBL25303281 | 0.74 | PIK3CA (0.32) | DHFRDCPSPIK3CAPIK3CBMTOR | |
| SCHEMBL23500593 | 0.73 | ILK (0.39) | PIK3CAPIK3R1PIK3CBPIK3CDPIK3CG | |
| SCHEMBL23500886 | 0.70 | TLR8 (0.40) | DHFR | |
| SCHEMBL29653649 | 0.67 | KCNH2 (0.43) | DHFRDCPSKCNH2PIK3CDPIK3CG | |
| SCHEMBL23514151 | 0.67 | KCNH2 (0.43) | DHFRDCPSKCNH2PIK3CDPIK3CG | |
| SCHEMBL23500818 | 0.67 | DHFR (0.35) | DHFRDCPS | |
| SCHEMBL29197978 | 0.67 | HRH4 (0.42) | DHFRDCPSPIK3CAMTOR | |
| SCHEMBL2634024 | 0.66 | DHFR (0.42) | DHFRDCPS | |
| SCHEMBL23500745 | 0.65 | HSD17B10 (0.33) | DHFRDCPSKCNH2PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021114691-A1 | NITROGEN-CONTAINING RING-FUSED COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-06-17 | — | — | WO | disclosed |