Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30776740 | 0.77 | KCNH2 (0.33) | PIK3CAPIK3CBMTORDHFRDCPS | |
| SCHEMBL23500856 | 0.74 | DHFR (0.43) | PIK3CAPIK3CBMTORDHFRDCPS | |
| SCHEMBL30598845 | 0.73 | SELE (0.33) | — | |
| SCHEMBL1694118 | 0.65 | DHFR (0.36) | PIK3CAPIK3CBAKT1MTORDHFR | |
| SCHEMBL18978713 | 0.62 | GRM4 (0.36) | DHFRDCPS | |
| SCHEMBL3386121 | 0.62 | MAPK1 (0.38) | PIK3CAPIK3CBAKT1MTORDHFR | |
| SCHEMBL31270725 | 0.62 | KCNH3 (0.41) | PIK3CAMTOR | |
| SCHEMBL25818890 | 0.62 | KCNH3 (0.41) | PIK3CAMTOR | |
| SCHEMBL1693802 | 0.60 | MAPK1 (0.46) | DHFRDCPS | |
| SCHEMBL23910454 | 0.60 | MAPK1 (0.35) | PIK3CAAKT1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023207710-A1 | ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |