Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.46 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.43 |
| ▸ | SELP | P16109 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29934010 | 0.88 | HDAC8 (0.48) | HDAC8HDAC1HDAC6L3MBTL1DDR1 | |
| SCHEMBL23501655 | 0.88 | HDAC8 (0.48) | HDAC8HDAC1HDAC6L3MBTL1DDR1 | |
| SCHEMBL28884708 | 0.81 | HDAC8 (0.49) | HDAC8HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL29933875 | 0.81 | HDAC8 (0.49) | HDAC8HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL29933394 | 0.80 | TAS1R3 (0.47) | HDAC8HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL29934023 | 0.77 | ALDH1A1 (0.64) | HDAC8HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL28884580 | 0.77 | ALDH1A1 (0.64) | HDAC8HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL23501594 | 0.75 | POLB (0.44) | POLBHCAR2KDM4EALDH1A1PKM | |
| SCHEMBL31359391 | 0.75 | PKM (0.51) | POLBHCAR2PKMSMN1; SMN2 | |
| SCHEMBL29934040 | 0.75 | POLB (0.44) | POLBHCAR2KDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021117846-A1 | COMPOUND SERVING AS PDGF RECEPTOR KINASE INHIBITOR, AND COMPOSITION | 日本新薬株式会社 | 2021-06-17 | — | — | WO | disclosed |