Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.48 |
| ▸ | MAP3K5 | Q99683 | 12/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21937449 | 0.85 | MCHR1 (0.60) | SCN10AMCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL798511 | 0.80 | MCHR1 (0.45) | SCN10AMCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL15172662 | 0.79 | SCN10A (0.61) | SCN10AMCHR1MAP3K5CSNK1DCSNK1G2 | |
| SCHEMBL10022336 | 0.78 | NPC1 (0.52) | SCN10AMCHR1MAP3K5KDM4ENPC1 | |
| SCHEMBL15172730 | 0.77 | SCN10A (1.00) | SCN10AMCHR1MAP3K5ALDH1A1SMN1; SMN2 | |
| SCHEMBL12269176 | 0.77 | SCN10A (0.40) | SCN10AMCHR1KDM4ENPC1ALDH1A1 | |
| SCHEMBL15828624 | 0.77 | SCN10A (0.48) | SCN10AMCHR1MAP3K5CSNK1DCSNK1G2 | |
| SCHEMBL2707031 | 0.77 | MCHR1 (0.49) | SCN10AMCHR1MAP3K5CSNK1DCSNK1G2 | |
| SCHEMBL12197120 | 0.75 | APP (0.46) | SCN10AMCHR1MAP3K5KDM4ENPC1 | |
| SCHEMBL14701750 | 0.75 | MCHR1 (0.41) | SCN10AMCHR1KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220372033-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-11-24 | — | — | US | disclosed |
| US-11033539-B2 | Compounds of formulas (VII), (VIII), (IX), (XI), (XII), (XIII), and (XIV) as muscarinic receptor 4(M4) antagonists for treating neurological diseases | NEUROCRINE BIOSCIENCES, INC. (US) | 2021-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11033539-B2 | Compounds of formulas (VII), (VIII), (IX), (XI), (XII), (XIII), and (XIV) as muscarinic receptor 4(M4) antagonists for treating neurological diseases | CHRM2, CHRM4, CHRM1 | SCN10A 1900/4885MCHR1 167/4885MAP3K5 2424/4885 |
| US-20220372033-A1 | ANTIBACTERIAL COMPOUNDS | NDUFS3, SQOR, MT-ND4 | SCN10A 4645/4885MCHR1 4500/4885MAP3K5 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.