Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21702028 | 1.00 | CTSL (0.49) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL23506399 | 0.96 | CTSK (0.49) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL21702026 | 0.96 | CTSK (0.49) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL21702031 | 0.92 | CTSL (0.49) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL21702029 | 0.90 | CTSL (0.50) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL23712032 | 0.90 | CTSL (0.50) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL23711634 | 0.89 | CTSK (0.51) | CTSLCTSSCTSKCTSB | |
| SCHEMBL23506521 | 0.89 | CTSK (0.51) | CTSLCTSSCTSKCTSB | |
| SCHEMBL21702268 | 0.89 | MEN1 (0.46) | CTSLCTSSCTSKRENCTSB | |
| SCHEMBL23712029 | 0.89 | CTSL (0.49) | CTSLCTSSCTSKRENCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151387-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | 中国科学院上海药物研究所 | 2021-08-05 | — | — | WO | disclosed |
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |