Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19605969 | 0.93 | CTSB (0.38) | CTSLCTSBCTSS | |
| SCHEMBL19606017 | 0.86 | CTSL (0.40) | CTSLCTSBCTSS | |
| SCHEMBL24690561 | 0.85 | — | — | |
| SCHEMBL24029103 | 0.85 | CTSL (0.42) | CTSLCTSB | |
| SCHEMBL24020662 | 0.82 | CTSL (0.39) | CTSLCTSB | |
| SCHEMBL26223290 | 0.82 | CTSL (0.39) | CTSLCTSB | |
| SCHEMBL29169940 | 0.82 | CCR2 (0.40) | CTSLCTSB | |
| SCHEMBL29169941 | 0.82 | CCR2 (0.40) | CTSLCTSB | |
| SCHEMBL21702235 | 0.81 | CTSL (0.42) | CTSLCTSB | |
| SCHEMBL23824587 | 0.81 | CTSL (0.44) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256434-A1 | PROTEASE INHIBITORS AS ANTIVIRALS | ACEA Therapeutics, Inc. (US) | 2022-12-08 | — | — | WO | disclosed |
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |