Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.52 |
| ▸ | ACACA | Q13085 | 12/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2351679 | 0.89 | ACACB (0.40) | ACACBACACAPGRPTGS2EDNRB | |
| SCHEMBL2350099 | 0.87 | ACACB (0.51) | ACACBACACAPGRPTGS2EDNRB | |
| SCHEMBL14066574 | 0.84 | ACACB (0.38) | ACACBACACAPGRPTGS2EDNRA | |
| SCHEMBL2352301 | 0.82 | ACACB (0.52) | ACACBACACAPGRPTGS2EDNRB | |
| SCHEMBL2350565 | 0.81 | ACACB (0.47) | ACACBACACAPGRPTGS2EDNRB | |
| SCHEMBL14066722 | 0.81 | ACACB (0.36) | ACACBACACAPGRPTGS2EDNRA | |
| SCHEMBL2356692 | 0.80 | ACACB (0.49) | ACACBACACACNR1CNR2 | |
| SCHEMBL2349821 | 0.80 | ACACB (0.49) | ACACBACACACNR1CNR2 | |
| SCHEMBL14066724 | 0.79 | MALT1 (0.36) | ACACBACACAPTGS2CA9 | |
| SCHEMBL2361957 | 0.79 | ACACB (0.48) | ACACBACACAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-14 | — | — | US | disclosed |
| EP-2536686-A1 | CYCLIC KETO-ENOLS FOR THERAPY | Bayer Intellectual Property GmbH (DE) | 2012-12-26 | — | — | EP | disclosed |
| US-8247351-B2 | Insecticidal compositions having improved effect | BAYER CROPSCIENCE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-8247351-B2 | Insecticidal compositions having improved effect | BAYER CROPSCIENCE AG (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20120129833-A1 | CYCLIC KETOENOLS FOR THERAPY | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129833-A1 | CYCLIC KETOENOLS FOR THERAPY | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120129833-A1 | CYCLIC KETOENOLS FOR THERAPY | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2011098433-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011098433-A1 | CYCLIC KETO-ENOLS FOR THERAPY | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-08-18 | — | — | WO | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | BAYER CROPSCIENCE AG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20080026943-A1 | Phenyl-Substituted [1,2]-Oxazine-3,5-Dione and Dihydropyrone Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20080026943-A1 | Phenyl-Substituted [1,2]-Oxazine-3,5-Dione and Dihydropyrone Derivatives | BAYER CROPSCIENCE AG (DE) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040935-A1 | CYCLIC KETO-ENOLS FOR THERAPY | AKR1B1, AKR1C3, AKR1A1 | ACACB 310/4885ACACA 541/4885PGR 305/4885 |
| US-20110294783-A1 | Insecticidal Compositions Having Improved Effect | FASN, CYP51A1, PIKFYVE | ACACB 58/4885ACACA 41/4885PGR 3045/4885 |
| US-20120129833-A1 | CYCLIC KETOENOLS FOR THERAPY | CYP46A1, LIPC, CYP27A1 | ACACB 85/4885ACACA 90/4885PGR 1372/4885 |
| US-20090209513-A1 | Insecticidal Compositions Having Improved Effect | PTEN, PIK3CG, PIK3CD | ACACB 632/4885ACACA 382/4885PGR 2614/4885 |
| US-20080026943-A1 | Phenyl-Substituted [1,2]-Oxazine-3,5-Dione and Dihydropyrone Derivatives | DDT, CYP1A1, CYP1B1 | ACACB 1802/4885ACACA 2203/4885PGR 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.