SCHEMBL23510046

SCHEMBL23510046

CCCCc1ccc(B2OC(C)(C)C(C)(C)O2)c(C(C)=O)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 7/20 0.49
LPL P06858 6/20 0.49
KAT8 Q9H7Z6 2/20 0.41
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SKP2 Q13309 1/20 0.37
METAP2 P50579 1/20 0.37
POLB P06746 1/20 0.36
PPARG P37231 1/20 0.36
F2 P00734 1/20 0.36
F11 P03951 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
RARB P10826 1/20 0.35
PLK1 P53350 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21362597 0.76 LPL (0.43) LIPGLPLPPARARARBPLK1
SCHEMBL22748425 0.76 LPL (0.61) LIPGLPLKAT8PPARAALDH1A1
SCHEMBL22748787 0.76 LPL (0.61) LIPGLPLKAT8PPARAALDH1A1
SCHEMBL21362596 0.75 LPL (0.42) LIPGLPLALDH1A1RARBPLK1
SCHEMBL16166586 0.75 CA12 (0.40) ALDH1A1HSD17B10
SCHEMBL24265381 0.75 CXCR2 (0.43) LIPGLPLALDH1A1F2F11
SCHEMBL22748371 0.74 LPL (0.62) LIPGLPLKAT8PPARAALDH1A1
SCHEMBL22748361 0.74 LPL (0.62) LIPGLPLKAT8PPARAALDH1A1
SCHEMBL22748247 0.73 LPL (0.61) LIPGLPLKAT8PPARAALDH1A1
SCHEMBL22748772 0.73 LPL (0.61) LIPGLPLALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639471-B2 Compound, liquid crystal composition and high-frequency phase shifter DIC CORPORATION (JP) 2023-05-02 US disclosed
US-11639471-B2 Compound, liquid crystal composition and high-frequency phase shifter DIC CORPORATION (JP) 2023-05-02 US disclosed
US-20210179943-A1 COMPOUND, LIQUID CRYSTAL COMPOSITION AND HIGH-FREQUENCY PHASE SHIFTER DIC CORPORATION (JP) 2021-06-17 US disclosed