Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.43 |
| ▸ | PLK1 | P53350 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362596 | 0.90 | LPL (0.42) | LPLLIPGPLK1CNR2RARB | |
| SCHEMBL20157811 | 0.83 | SRD5A2 (0.36) | SRD5A2 | |
| SCHEMBL20157690 | 0.82 | SRD5A2 (0.37) | SRD5A2 | |
| SCHEMBL20158134 | 0.81 | SRD5A2 (0.35) | SRD5A2 | |
| SCHEMBL20157897 | 0.80 | SRD5A2 (0.36) | SRD5A2 | |
| SCHEMBL21362721 | 0.79 | SRD5A2 (0.35) | SRD5A2 | |
| SCHEMBL5414465 | 0.78 | LPL (0.55) | LPLLIPGPLK1PLK3RARB | |
| SCHEMBL20157444 | 0.77 | MEN1 (0.37) | LPLLIPGPLK1CNR2 | |
| SCHEMBL20157806 | 0.76 | HTT (0.49) | — | |
| SCHEMBL23510046 | 0.76 | LIPG (0.49) | LPLLIPGPLK1RARBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |