Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAP2 | P11137 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | FRK | P42685 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23511153 | 0.81 | ALDH1A1 (0.66) | CSF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30043900 | 0.81 | MAPT (0.55) | CSF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL23498271 | 0.81 | MAPT (0.55) | CSF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30043560 | 0.75 | MAP2 (0.74) | CSF1RALDH1A1MAPTMAP2ATM | |
| SCHEMBL6059495 | 0.75 | MAP2 (0.74) | CSF1RALDH1A1MAPTMAP2ATM | |
| SCHEMBL23498272 | 0.74 | CSF1R (0.49) | CSF1RMAP2KDM4EGSK3BHPGD | |
| SCHEMBL30044896 | 0.74 | CSF1R (0.49) | CSF1RMAP2KDM4EGSK3BHPGD | |
| SCHEMBL31139832 | 0.73 | SIRT1 (0.52) | CSF1RMAP2KDM4EGSK3BPTGS2 | |
| SCHEMBL25430492 | 0.73 | SIRT1 (0.52) | CSF1RMAP2KDM4EGSK3BPTGS2 | |
| SCHEMBL23510959 | 0.73 | GRIN2D (0.58) | CSF1RALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021116999-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF TUMORS | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2021-06-17 | — | — | WO | disclosed |