Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23512612 | 1.00 | FFAR1 (0.60) | FFAR1S1PR1S1PR5GPR88ALDH1A1 | |
| SCHEMBL10267695 | 0.95 | FFAR1 (0.55) | FFAR1ALDH1A1 | |
| SCHEMBL25146666 | 0.83 | FFAR1 (0.56) | FFAR1S1PR1S1PR5GPR88FFAR4 | |
| SCHEMBL12646402 | 0.81 | FFAR1 (0.73) | FFAR1S1PR1S1PR5GPR88ALDH1A1 | |
| SCHEMBL7868639 | 0.81 | FFAR1 (0.68) | FFAR1GPR88ALDH1A1FFAR4RXRA | |
| SCHEMBL6994406 | 0.81 | FFAR1 (0.68) | FFAR1GPR88ALDH1A1FFAR4RXRA | |
| SCHEMBL25146532 | 0.80 | FFAR1 (0.56) | FFAR1FFAR4 | |
| SCHEMBL15096176 | 0.80 | FFAR1 (0.56) | FFAR1GPR88ALDH1A1 | |
| SCHEMBL14079556 | 0.78 | GPR88 (0.41) | FFAR1S1PR1S1PR5GPR88ALDH1A1 | |
| SCHEMBL3421589 | 0.76 | CYP4F2 (0.47) | FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |