Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.68 |
| ▸ | KDM1A | O60341 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994406 | 1.00 | FFAR1 (0.68) | FFAR1KDM1AMAOBHDAC4ALDH1A1 | |
| SCHEMBL323824 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL5217474 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL1172743 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL2034678 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL4126470 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL5315326 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL8295172 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL323823 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL3359435 | 0.88 | FFAR1 (0.70) | FFAR1HDAC4ALDH1A1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251910-B1 | 1,2,3-triazolo[4,5-d]pyrimidines as P2T receptor antagonists | ASTRAZENECA UK LIMITED (GB) | 2001-06-26 | — | — | US | disclosed |