Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23512759 | 0.80 | FFAR1 (0.60) | FFAR1FFAR4 | |
| SCHEMBL23512612 | 0.80 | FFAR1 (0.60) | FFAR1FFAR4 | |
| SCHEMBL6994406 | 0.77 | FFAR1 (0.68) | FFAR1FFAR4 | |
| SCHEMBL7868639 | 0.77 | FFAR1 (0.68) | FFAR1FFAR4 | |
| SCHEMBL25146666 | 0.77 | FFAR1 (0.56) | FFAR1FFAR4 | |
| SCHEMBL15096176 | 0.76 | FFAR1 (0.56) | FFAR1CYP4F2CYP4A11 | |
| SCHEMBL10267695 | 0.74 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL12646402 | 0.74 | FFAR1 (0.73) | FFAR1FFAR4 | |
| SCHEMBL3734035 | 0.72 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL13043487 | 0.72 | FFAR1 (1.00) | FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | PPID, PPIF, PPIL1 | FFAR1 776/4885FFAR4 2102/4885CYP4F2 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.