Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23512830 | 0.88 | POLB (0.49) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL23512926 | 0.74 | POLB (0.52) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL16437764 | 0.74 | POLB (0.49) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL23512775 | 0.74 | POLB (0.56) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL10824751 | 0.69 | SGMS2 (0.49) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL10590979 | 0.69 | POLB (0.56) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL16587496 | 0.68 | SMN1; SMN2 (0.46) | POLBALDH1A1USP2TSHRHSD17B10 | |
| SCHEMBL8370127 | 0.68 | LMNA (0.53) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL31643796 | 0.68 | L3MBTL1 (0.53) | POLBALDH1A1TSHRLMNAGAA | |
| SCHEMBL15324624 | 0.68 | POLB (0.58) | POLBALDH1A1USP2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074709-A1 | MONOCYCLIC BETA-LACTAM COMPOUND AND USE THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2022-10-19 | — | — | EP | disclosed |
| WO-2021115444-A1 | MONOCYCLIC β-LACTAM COMPOUND AND USE THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-17 | — | — | WO | disclosed |