Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 10/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16407998 | 0.82 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL2185057 | 0.82 | PPARA (0.42) | PPARAPPARGPPARD | |
| SCHEMBL4388342 | 0.79 | ALOX15 (0.33) | ALOX15 | |
| SCHEMBL13591198 | 0.77 | — | — | |
| SCHEMBL8499223 | 0.77 | SLC1A3 (0.38) | PPARAALOX15PPARGPPARDLMNA | |
| Ethylene Glycol SCHEMBL3729359 | 0.77 | PPARA (0.39) | PPARAPPARGPPARD | |
| SCHEMBL10768520 | 0.77 | — | — | |
| SCHEMBL447796 | 0.77 | — | — | |
| SCHEMBL9843858 | 0.77 | — | — | |
| Aspartic Acid SCHEMBL23794557 | 0.76 | GRIK1 (0.44) | PPARAGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103018-A1 | SUBSTITUTED FUSED IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-08-25 | — | — | WO | disclosed |