SCHEMBL8499223

SCHEMBL8499223

COC(CC(N)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
SRR Q9GZT4 1/20 0.34
ECE1 P42892 3/20 0.33
PARP1 P09874 1/20 0.33
PARP10 Q53GL7 1/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PPARG P37231 2/20 0.32
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
LMNA P02545 1/20 0.32
LAP3 P28838 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6376109 0.83 L3MBTL1 (0.33) SLC1A3SLC1A2SLC1A1ECE1PARP1
SCHEMBL2593546 0.80 TDP1 (0.43) SLC1A3SLC1A2SLC1A1PARP1PARP10
SCHEMBL10212 0.80 TDP1 (0.43) SLC1A3SLC1A2SLC1A1PARP1PARP10
SCHEMBL2580759 0.80 TDP1 (0.43) SLC1A3SLC1A2SLC1A1PARP1PARP10
SCHEMBL6818331 0.79 SMN1; SMN2 (0.36) ECE1PARP1PARP10ALOX15KMT2A
SCHEMBL10029740 0.78 ALDH1A1 (0.42) SLC1A3SLC1A2SLC1A1SRRALDH1A1
SCHEMBL11672388 0.78 TDP1 (0.42) SLC1A3SLC1A2SLC1A1PARP1PARP10
SCHEMBL6742371 0.78 TDP1 (0.42) SLC1A3SLC1A2SLC1A1PARP1PARP10
SCHEMBL2351606 0.77 PPARA (0.40) ECE1ALOX15PPARGPPARDPPARA
SCHEMBL27554698 0.77 KDM4E (0.42) SLC1A3SLC1A2SLC1A1SRRPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0888289-A1 ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES Research Corporation Technologies, Inc (US) 1999-01-07 EP disclosed
WO-1997033861-A1 ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-09-18 WO disclosed