Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | MAX | P61244 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23516558 | 0.83 | HSD11B1 (0.36) | PIM1 | |
| SCHEMBL23516605 | 0.79 | HSD11B1 (0.38) | — | |
| SCHEMBL29762669 | 0.79 | HSD11B1 (0.38) | — | |
| SCHEMBL20556028 | 0.79 | TYR (0.44) | TYRPIM1POLBALDH1A3CYP2A6 | |
| SCHEMBL20556103 | 0.79 | TYR (0.44) | TYRPIM1POLBALDH1A3CYP2A6 | |
| SCHEMBL5586397 | 0.73 | CYP19A1 (0.36) | TYRALDH1A3CYP2A6ALDH1A1CYP2A13 | |
| SCHEMBL23516650 | 0.72 | TYR (0.41) | TYRPIM1POLBALDH1A3CYP2A6 | |
| SCHEMBL17172987 | 0.70 | OTUD7B (0.31) | — | |
| SCHEMBL7433600 | 0.70 | OTUD7B (0.31) | — | |
| SCHEMBL23836081 | 0.70 | OTUD7B (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021118887-A1 | CGRP ANTIGONISTS USEFUL AS TRACER COMPOUNDS FOR POSITRON EMISSION TOMOGRAPHY | ELI LILLY AND COMPANY (US) | 2021-06-17 | — | — | WO | disclosed |