Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23560093 | 0.87 | KDM5A (0.30) | KDM5A | |
| SCHEMBL23744365 | 0.74 | HTT (0.40) | — | |
| SCHEMBL23744343 | 0.72 | RAB9A (0.41) | — | |
| SCHEMBL23744362 | 0.72 | POLB (0.43) | — | |
| SCHEMBL27867751 | 0.70 | IRAK4 (0.36) | — | |
| SCHEMBL23806372 | 0.70 | IRAK4 (0.54) | — | |
| SCHEMBL25338181 | 0.69 | AAK1 (0.34) | — | |
| SCHEMBL25339977 | 0.69 | GFER (0.33) | KDM5A | |
| SCHEMBL25969171 | 0.69 | AAK1 (0.34) | — | |
| SCHEMBL25969167 | 0.69 | GFER (0.33) | KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119159-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-06-17 | — | — | WO | disclosed |