SCHEMBL27867751

SCHEMBL27867751

Cn1cc(NC=O)c(C(F)F)n1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 19/20 0.36
ALOX5AP P20292 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29016162 0.83 IRAK4 (0.36) IRAK4ALOX5AP
SCHEMBL19022064 0.78 IRAK4 (0.36) IRAK4ALOX5AP
SCHEMBL28954016 0.77 IRAK4 (0.38) IRAK4ALOX5AP
SCHEMBL28306067 0.77 FYN (0.35)
SCHEMBL28215132 0.74 LMNA (0.41)
SCHEMBL27467128 0.74 ADORA2A (0.37) IRAK4
SCHEMBL1586647 0.73 ALDH1A1 (0.33) IRAK4
SCHEMBL27710357 0.72 LMNA (0.40) IRAK4ALOX5AP
SCHEMBL23560093 0.72 KDM5A (0.30)
SCHEMBL23518784 0.70 KDM5A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138364-A Preparation method of fluorobenzene ether amide 东莞市东阳光菌阳氢专利农药有限公司 2020-05-12 CN disclosed
CN-111138364-A Preparation method of fluorobenzene ether amide 东莞市东阳光菌阳氢专利农药有限公司 2020-05-12 CN disclosed
CN-108699075-A Spirocyclic derivatives 巴斯夫欧洲公司 2018-10-23 CN disclosed
CN-108697089-A The method for preventing and kill off plant insect 巴斯夫欧洲公司 2018-10-23 CN disclosed
CN-102647903-A Pesticidal mixtures BASF SE 2012-08-22 CN disclosed