SCHEMBL2352483

SCHEMBL2352483

C=CCc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
HSD17B10 Q99714 1/20 0.47
LOXL2 Q9Y4K0 2/20 0.47
CYP2A6 P11509 1/20 0.47
MMP3 P08254 1/20 0.47
CYP3A4 P08684 2/20 0.43
CYP19A1 P11511 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
KIF11 P52732 3/20 0.42
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
IDO1 P14902 2/20 0.42
MMP12 P39900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7779660 1.00 TSHR (0.47) TSHRHSD17B10LOXL2CYP2A6MMP3
SCHEMBL991288 0.94 LOXL2 (0.52) TSHRLOXL2CYP2A6CYP3A4CYP19A1
Bromide SCHEMBL28224574 0.92 LOXL2 (0.50) TSHRLOXL2CYP2A6CYP3A4CYP19A1
SCHEMBL20045130 0.88 LOXL2 (0.48) TSHRLOXL2CYP2A6CYP3A4CYP19A1
SCHEMBL11212791 0.86 CYP1A2 (0.39) TSHRHSD17B10LOXL2CYP2A6MMP3
Water SCHEMBL28100235 0.85 ALDH1A1 (0.54) TSHRHSD17B10CYP3A4CYP1A2POLB
SCHEMBL8927518 0.85 HRH3 (0.57) HRH3
SCHEMBL10586609 0.84 CYP11B1 (0.48) TSHRHSD17B10CYP3A4CYP19A1CYP1A2
SCHEMBL9063036 0.83 ALDH1A1 (0.52) TSHRLOXL2CYP2A6CYP3A4CYP19A1
SCHEMBL584333 0.82 ALDH1A1 (0.56) TSHRHSD17B10CYP3A4CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745833-B Preparation method of 4-alkyl-4' -cyanobiphenyl 宁夏中星显示材料有限公司 2024-07-05 CN claimed
CN-115745833-A Preparation method of 4-alkyl-4' -cyanobiphenyl 宁夏中星显示材料有限公司 2023-03-07 CN claimed
US-7662572-B2 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC. (US) 2010-02-16 US claimed
US-7215491-B2 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2007-05-08 US claimed
US-20070099249-A1 Compositions and liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2007-05-03 US claimed
WO-2007025129-A2 COMPOSITIONS AND LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC. (US) 2007-03-01 WO claimed
US-20050248844-A1 Optical path switching device and method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE (JP) 2005-11-10 US claimed
US-6927823-B1 Method for alignment of liquid crystals using irradiated liquid crystal films KENT STATE UNIVERSITY (US) 2005-08-09 US claimed
EP-1540414-A1 OPTICAL PATH SWITCHING DEVICE AND METHOD National Institute of Advanced Industrial Science and Technology (JP) 2005-06-15 EP claimed
EP-0819305-B1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ELSICON INC (US) 2004-11-17 EP claimed
US-RE31715-E ESTERS OF 2-METHYLBUTYLPHENOL THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1984-10-30 US claimed
EP-0044646-B1 4-(TRANS-4'-ALKYLCYCLOHEXYL)BENZOIC ACID 4\"'-CYANO-4\"-BIPHENYLYL ESTERS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM Chisso Corporation (JP) 1984-04-18 EP claimed
US-4387039-A LIQUID CRYSTALS CHISSO CORPORATION (JP) 1983-06-07 US claimed
EP-0060646-A1 Liquid crystal compositions The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1982-09-22 EP claimed
US-4348298-A WITH DICHROIC DYESTUFF VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) 1982-09-07 US claimed
EP-0044646-A1 4-(Trans-4'-alkylcyclohexyl)benzoic acid 4\"'-cyano-4\"-biphenylyl esters and liquid crystal compositions containing them Chisso Corporation (JP) 1982-01-27 EP claimed
US-4206071-A Liquid crystal composition CHISSO CORPORATION (JP) 1980-06-03 US claimed
US-4195916-A ELECTROOPTIC DISPLAY DEVICES, OPTICAL PHENOLIC ESTERS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1980-04-01 US claimed
US-4119558-A PHENYL, NAPHTHYL DIESTERS OF CHLOROBENZENE DICARBOXYLIC ACID THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1978-10-10 US claimed
US-4113647-A ELECTRO-OPTIC DISPLAY DEVICE THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1978-09-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070099249-A1 Compositions and liquid crystals FABP5, FABP1, SSB TSHR 3633/4885HSD17B10 1353/4885LOXL2 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.