SCHEMBL23525317

SCHEMBL23525317

N[C@@H](CO)C(=O)OCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.49
TSHR P16473 1/20 0.49
MAOB P27338 1/20 0.48
HTT P42858 1/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HPGD P15428 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4A O75164 1/20 0.41
CYP2C19 P33261 2/20 0.41
POLB P06746 1/20 0.41
MGAM O43451 2/20 0.41
CTSD P07339 1/20 0.41
MAPT P10636 1/20 0.40
NPC1 O15118 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7897989 0.89 ALDH1A1 (0.46) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL7897985 0.89 ALDH1A1 (0.46) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL7897984 0.87 MAOB (0.47) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL1057910 0.87 KMT2A (0.51) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL2780596 0.87 MAOB (0.47) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL12869704 0.85 KDM4A (0.49) ALDH1A1TSHRMAOBHTTKDM4A
SCHEMBL12869702 0.85 MAOB (0.48) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL6865970 0.84 MAOB (0.52) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL28417854 0.84 ALDH1A1 (0.50) ALDH1A1TSHRMAOBHTTMEN1
SCHEMBL7865835 0.83 KDM4A (0.47) ALDH1A1TSHRMAOBHTTKDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117751409-A Method for optimizing protein production 英国研究与创新署 2024-03-22 CN disclosed
US-20210188971-A1 MONOCLONAL ANTIBODY FUSIONS QUIDEL CORPORATION 2021-06-24 US disclosed
CN-102827827-B Orthogonal translation components for in vivo incorporation of unnatural amino acids SCRIPPS RESEARCH INST (US) 2014-10-29 CN disclosed
CN-101048506-B Orthogonal translation Components for in vivo incorporation of unnatural amino acids SCRIPPS RESEARCH INST 2013-06-26 CN disclosed
CN-102827827-A Orthogonal translation components for in vivo incorporation of unnatural amino acids SCRIPPS RESEARCH INST 2012-12-19 CN disclosed
CN-101048506-A Orthogonal translation Components for in vivo incorporation of unnatural amino acids SCRIPPS RESEARCH INST (US) 2007-10-03 CN disclosed