Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393254 | 1.00 | KDM4A (0.47) | KDM4AMAOBALDH1A1SLC7A5HDAC8 | |
| SCHEMBL12869704 | 0.92 | KDM4A (0.49) | KDM4AMAOBALDH1A1SLC7A5MMP2 | |
| Tyrosine SCHEMBL7373359 | 0.85 | SLC7A5 (0.57) | KDM4AMAOBALDH1A1SLC7A5 | |
| SCHEMBL23525317 | 0.83 | ALDH1A1 (0.49) | KDM4AMAOBALDH1A1HTTMAPT | |
| Tyrosine SCHEMBL27680838 | 0.82 | KDM4A (0.64) | KDM4AMAOBSLC7A5NPC1RAB9A | |
| SCHEMBL1057910 | 0.82 | KMT2A (0.51) | KDM4AMAOBALDH1A1HTTTSHR | |
| SCHEMBL7897984 | 0.82 | MAOB (0.47) | KDM4AMAOBALDH1A1HTTMAPT | |
| SCHEMBL2780596 | 0.82 | MAOB (0.47) | KDM4AMAOBALDH1A1HTTMAPT | |
| SCHEMBL7897985 | 0.81 | ALDH1A1 (0.46) | KDM4AMAOBALDH1A1HTTMAPT | |
| SCHEMBL7897989 | 0.81 | ALDH1A1 (0.46) | KDM4AMAOBALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300495-B1 | REACTING ORGANIC AMINE SALT OF CLAVULANIC ACID WITH METAL SALT IN LIQUID MEDIUM OF FLUORINATED AND/OR CHLORINATED HYDROCARBON | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-10-09 | — | — | US | disclosed |
| EP-0970087-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998045300-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |
| EP-0804441-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022296-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-07-25 | — | — | WO | disclosed |