SCHEMBL2352987

SCHEMBL2352987

COc1cccc(C(O)C2=C(C)C2)c1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ AOC3 Q16853 3/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ BRD4 O60885 1/20 0.44
▸ ACHE P22303 1/20 0.44
▸ PKM P14618 1/20 0.44
▸ CHRM2 P08172 1/20 0.43
▸ CHRM1 P11229 1/20 0.43
▸ CHRM3 P20309 1/20 0.43
▸ IDO1 P14902 1/20 0.42
▸ TDO2 P48775 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ NPC1 O15118 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ SLC6A2 P23975 1/20 0.41
▸ SLC6A4 P31645 1/20 0.41
▸ KDM4A O75164 1/20 0.41
▸ KDM4C Q9H3R0 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093768 0.84 AOC3 (0.59) AOC3L3MBTL1BRD4ACHEPKM
SCHEMBL27686957 0.79 AOC3 (0.54) AOC3L3MBTL1BRD4PKMCHRM2
SCHEMBL4822561 0.79 AOC3 (0.54) AOC3L3MBTL1BRD4ACHEPKM
SCHEMBL477338 0.79 AOC3 (0.54) AOC3L3MBTL1BRD4PKMCHRM2
SCHEMBL11604883 0.76 AOC3 (0.62) AOC3L3MBTL1ACHECHRM2CHRM1
SCHEMBL2087869 0.76 AOC3 (0.59) AOC3L3MBTL1ACHECHRM2CHRM1
SCHEMBL17064808 0.76 ALDH1A1 (0.66) AOC3L3MBTL1BRD4PKMCHRM2
SCHEMBL31067514 0.76 ALDH1A1 (0.66) AOC3L3MBTL1BRD4PKMCHRM2
SCHEMBL10928081 0.75 AOC3 (0.48) AOC3L3MBTL1BRD4PKMCHRM2
SCHEMBL18529828 0.75 AOC3 (0.50) AOC3L3MBTL1BRD4PKMCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110190137-A1 METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS JACOBSON RICHARD MARTIN 2011-08-04 — — US disclosed
EP-1409440-A4 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM & HAAS (US) 2005-09-14 — — EP disclosed
US-20050065033-A1 Method to inhibit ethylene responses in plants JACOBSON RICHARD MARTIN (US) 2005-03-24 — — US disclosed
EP-1409440-A1 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM AND HAAS COMPANY (US) 2004-04-21 — — EP disclosed
WO-2002068367-A1 A METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ROHM AND HAAS COMPANY (US) 2002-09-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065033-A1 Method to inhibit ethylene responses in plants ERN1, CTH, CBS AOC3 771/4885L3MBTL1 1952/4885BRD4 2827/4885
US-20110190137-A1 METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ERN1, CTH, CBR3 AOC3 739/4885L3MBTL1 2001/4885BRD4 2773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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