SCHEMBL2353041

SCHEMBL2353041

O=C(OCC1=CC1)c1ccco1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
KMT2A Q03164 4/20 0.53
HTT P42858 1/20 0.52
ALDH1A1 P00352 9/20 0.50
HPGD P15428 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TSHR P16473 3/20 0.49
MEN1 O00255 2/20 0.49
HSD17B10 Q99714 1/20 0.49
KDM4E B2RXH2 2/20 0.48
NPC1 O15118 1/20 0.47
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN6 P29350 1/20 0.46
PTPN11 Q06124 1/20 0.46
POLB P06746 1/20 0.46
MAPK10 P53779 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2354998 0.84 ALDH1A1 (0.51) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL7863830 0.81 KMT2A (0.61) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL179961 0.79 ALDH1A1 (0.64) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL11039202 0.78 ALDH1A1 (0.62) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL30452406 0.78 ALDH1A1 (0.55) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL790857 0.77 KMT2A (0.60) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL4688815 0.77 KMT2A (0.60) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL27770727 0.77 KMT2A (0.60) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL27859868 0.76 ALDH1A1 (0.56) LMNAKMT2AHTTALDH1A1HPGD
SCHEMBL15256939 0.75 ALDH1A1 (0.59) LMNAKMT2AHTTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110190137-A1 METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS JACOBSON RICHARD MARTIN 2011-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190137-A1 METHOD TO INHIBIT ETHYLENE RESPONSES IN PLANTS ERN1, CTH, CBR3 LMNA 4062/4885KMT2A 3641/4885HTT 4181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.