Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958593 | 0.86 | ATM (0.43) | ATMRAB9AABL1RIN1TDP1 | |
| SCHEMBL29958628 | 0.85 | RAB9A (0.41) | RAB9APTGDR2 | |
| SCHEMBL23532005 | 0.74 | MEN1 (0.40) | ATMRAB9AABL1RIN1TDP1 | |
| SCHEMBL23532074 | 0.72 | ABL1 (0.41) | ATMRAB9AABL1RIN1TDP1 | |
| SCHEMBL29958557 | 0.72 | ALOX5 (0.48) | ATMRAB9A | |
| SCHEMBL23532060 | 0.72 | RAB9A (0.60) | ATMRAB9AABL1RIN1TDP1 | |
| SCHEMBL29958779 | 0.71 | SLC22A12 (0.43) | TDP1MEN1GAAKMT2AHPGD | |
| SCHEMBL29958832 | 0.71 | ALOX5 (0.36) | RAB9AGAASMN1; SMN2LMNATTR | |
| SCHEMBL23532077 | 0.69 | TDP1 (0.45) | ATMRAB9AABL1RIN1TDP1 | |
| SCHEMBL11233136 | 0.68 | ATM (0.54) | ATMRAB9AABL1RIN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077324-A1 | NOVEL COMPOUNDS AND THEIR USE | Debiopharm International SA (CH) | 2022-10-26 | — | — | EP | claimed |
| WO-2021123372-A1 | NOVEL COMPOUNDS AND THEIR USE | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2021-06-24 | — | — | WO | claimed |