Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12243237 | 0.88 | S1PR1 (0.50) | S1PR1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL12243261 | 0.87 | S1PR1 (0.56) | S1PR1NPC1RAB9AS1PR3SCD5 | |
| SCHEMBL12243119 | 0.83 | S1PR1 (0.45) | S1PR1NPC1RAB9AS1PR3KMT2A | |
| SCHEMBL15214831 | 0.82 | ALDH1A1 (0.56) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL1790000 | 0.81 | ALDH1A1 (0.59) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL2949436 | 0.81 | ALDH1A1 (0.59) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL2944396 | 0.81 | ALDH1A1 (0.59) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL5203862 | 0.80 | NPC1 (0.65) | MAPTTP53NPC1RAB9AALDH1A1 | |
| SCHEMBL12171876 | 0.80 | RAB9A (0.61) | MAPTTP53NPC1RAB9AALDH1A1 | |
| SCHEMBL5205950 | 0.80 | NPC1 (0.65) | MAPTTP53NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921309-B2 | Lipopeptide compounds and their use | UNIQUEST PTY LIMITED (AU) | 2014-12-30 | — | — | US | disclosed |
| EP-2350119-B1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | UNIQUEST PTY LTD (AU) | 2014-10-29 | — | — | EP | disclosed |
| EP-2350119-A1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | Merlion Pharmaceuticals Pte Ltd. (SG) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010062264-A1 | LIPOPEPTIDE COMPOUNDS AND THEIR USE | MERLION PHARMACEUTICALS PTE LTD (SG) | 2010-06-03 | — | — | WO | disclosed |