Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203862 | 1.00 | NPC1 (0.65) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL5209891 | 0.90 | NPC1 (0.57) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL960012 | 0.89 | NPC1 (0.52) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL16221391 | 0.89 | CA12 (0.57) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL12171876 | 0.89 | RAB9A (0.61) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL12171571 | 0.89 | RAB9A (0.61) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL12171609 | 0.87 | PTGS2 (0.56) | NPC1RAB9APTGS2MAPTTP53 | |
| SCHEMBL12171837 | 0.87 | PTGS2 (0.56) | NPC1RAB9APTGS2MAPTTP53 | |
| SCHEMBL5209165 | 0.87 | NPC1 (0.60) | NPC1RAB9AMAPTTP53CXCR1 | |
| SCHEMBL5206716 | 0.87 | NPC1 (0.60) | NPC1RAB9AMAPTTP53CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | NPC1 828/4885RAB9A 1448/4885CASP3 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.