Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.69 |
| ▸ | TSHR | P16473 | 6/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL8845165 | 0.94 | TSHR (0.69) | ACHETSHRLMNAALOX12NPSR1 | |
| Toluene SCHEMBL4498352 | 0.90 | TSHR (0.73) | ACHETSHRLMNAALOX12NPSR1 | |
| Toluene SCHEMBL10989418 | 0.90 | — | — | |
| Toluene SCHEMBL11250184 | 0.87 | — | — | |
| Toluene SCHEMBL11348456 | 0.87 | — | — | |
| Toluene SCHEMBL31493144 | 0.87 | ACHE (0.92) | ACHETSHRLMNAALOX12NPSR1 | |
| Toluene SCHEMBL5141031 | 0.83 | — | — | |
| Toluene SCHEMBL7062875 | 0.83 | ACHE (0.85) | ACHETSHRLMNAALOX12NPSR1 | |
| Toluene SCHEMBL8938900 | 0.83 | ACHE (1.00) | ACHETSHRLMNAALOX12NPSR1 | |
| Toluene SCHEMBL4535818 | 0.83 | ACHE (1.00) | ACHETSHRLMNAALOX12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426617-B2 | Asymmetric hydrogenation of alkenes using chiral iridium complexes | DSM IP ASSETS B.V. (NL) | 2013-04-23 | — | — | US | disclosed |
| EP-1828159-B1 | ASYMMETRIC HYDROGENATION OF ALKENES USING CHIRAL IRIDIUM COMPLEXES | DSM IP ASSETS BV (NL) | 2011-08-17 | — | — | EP | disclosed |
| US-20080039638-A1 | Asymmetric Hydrogenation of Alkennes Using Chiral Iridium Complexes | DSM IP ASSETS B.V. (NL) | 2008-02-14 | — | — | US | disclosed |
| EP-1828159-A1 | ASYMMETRIC HYDROGENATION OF ALKENES USING CHIRAL IRIDIUM COMPLEXES | DSMIP Assets B.V. (NL) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066863-A1 | ASYMMETRIC HYDROGENATION OF ALKENNES USING CHIRAL IRIDIUM COMPLEXES | DSM IP ASSETS B.V. (NL) | 2006-06-29 | — | — | WO | disclosed |
| US-6048908-A | POROUS CROSSLINKED ADDITION POLYMER MICROBEADS FOR ABSORBERS OR CARRIERS | BIOPORE CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |
| US-4393103-A | APPLYING AQUEOUS DISPERSION OF RIGID POLYMER, FILLER, AND ORGANIC TIN COMPOUND | LOUDEN WILLIAM G | 1983-07-12 | — | — | US | disclosed |
| US-4232083-A | COLOR PRECURSOR, ACTIVATORS, FINGERPRINTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4066802-A | DECALCOMANIA, POLYMERIC PLASTICIZING MATERIAL | XEROX CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039638-A1 | Asymmetric Hydrogenation of Alkennes Using Chiral Iridium Complexes | SQLE, FADS1, FADS2 | ACHE 1348/4885TSHR 3065/4885LMNA 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.