Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.73 |
| ▸ | ACHE | P22303 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL10989418 | 0.93 | — | — | |
| Toluene SCHEMBL8845165 | 0.90 | TSHR (0.69) | TSHRACHELMNAALOX12TDP1 | |
| Toluene SCHEMBL2353255 | 0.90 | ACHE (0.69) | TSHRACHELMNAALOX12TDP1 | |
| Toluene SCHEMBL11250184 | 0.89 | — | — | |
| Toluene SCHEMBL31493144 | 0.89 | ACHE (0.92) | TSHRACHELMNAALOX12TDP1 | |
| Toluene SCHEMBL11348456 | 0.89 | — | — | |
| Toluene SCHEMBL5141031 | 0.86 | — | — | |
| Toluene SCHEMBL7062875 | 0.86 | ACHE (0.85) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL12344943 | 0.86 | ACHE (1.00) | TSHRACHELMNAALOX12TDP1 | |
| Toluene SCHEMBL8824270 | 0.86 | ACHE (1.00) | TSHRACHELMNAALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1250329-C | Endotoxin adsorbing agent and preparing method thereof | UNIV NANKAI (CN) | 2006-04-12 | — | — | CN | claimed |
| CN-1239210-C | Endotoxin absorbing agent for blood perfusion and its preparation method | UNIV NANKAI (CN) | 2006-02-01 | — | — | CN | claimed |
| CN-1528511-A | Endotoxin adsorbing agent and preparing method thereof | 南开大学 | 2004-09-15 | — | — | CN | claimed |
| CN-1493368-A | Endotoxin absorbing agent for blood perfusion and its preparation method | 南开大学 | 2004-05-05 | — | — | CN | claimed |
| CN-115468923-A | Method for detecting ammonia value in amino silicone oil | 湖北兴瑞硅材料有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-106215819-B | The preparation method of konjak portuguese gansu polyose gel microsphere | 西南科技大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-104725536-B | A kind of low entanglement degree ultrahigh molecular weight polyethylene powder and its preparation method of sheet material | 宁波大学 | 2017-03-15 | — | — | CN | disclosed |
| CN-106215819-A | The preparation method of konjak portuguese gansu polyose gel microsphere | 西南科技大学 | 2016-12-14 | — | — | CN | disclosed |
| CN-101322933-B | Endotoxin absorbent and preparation thereof | ZHUHAI LIVZON PHARMACY MATERIAL CO LTD | 2011-08-10 | — | — | CN | disclosed |
| CN-101322934-B | Method for preparing endotoxin adsorbing agent | ZHUHAI LIVZON PHARMACY MATERIAL CO LTD | 2010-09-29 | — | — | CN | disclosed |
| US-7582626-B2 | 5,6-dihydro-1H-pyridin-2-one compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20090111798-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. | 2009-04-30 | — | — | US | disclosed |
| EP-0257419-A1 | Process for the preparation of antibacterial 7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0240632-A2 | Heat-shrinkable biaxially drawn polyamide film and process for preparaton thereof | MITSUBISHI KASEI POLYTEC COMPANY (JP) | 1987-10-14 | — | — | EP | disclosed |
| US-4622315-A | AROMATIC NITRO COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0198326-A2 | Poly-p-phenylene-terephthalamide film and process for producing the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-10-22 | — | — | EP | disclosed |
| US-4535901-A | ADHESIVES FOR RUBBER-MTTAL ADHESION/ VERING MIDDLE THERMOPLASTIC ONES; HYGIENE | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1985-08-20 | — | — | US | disclosed |
| US-4370468-A | Biaxially drawn polyhexamethylene adipamide film | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-01-25 | — | — | US | disclosed |
| US-4352926-A | ISOTROPIC, TOUGHNESS, HEAT RESISTANCE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-10-05 | — | — | US | disclosed |
| US-4252966-A | Biaxially drawn polyhexamethylene adipamide film | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111798-A1 | 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS | HAVCR2, PYGL, HCCS | TSHR 4518/4885ACHE 1582/4885LMNA 1248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.