SCHEMBL23533293

SCHEMBL23533293

CCCCCC1C(CCCOCc2ccccc2)C1(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 2/20 0.40
ALDH1A1 P00352 3/20 0.39
CETP P11597 3/20 0.38
HRH3 Q9Y5N1 3/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
HRH4 Q9H3N8 1/20 0.37
HPGD P15428 1/20 0.37
GBA1 P04062 2/20 0.36
UGCG Q16739 2/20 0.36
GBA2 Q9HCG7 2/20 0.36
EPHX2 P34913 1/20 0.36
PTPN1 P18031 1/20 0.36
CDC25B P30305 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23533466 0.93 CETP (0.40) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL23533480 0.87 L3MBTL1 (0.40) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL941253 0.81 TSHR (0.56) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL23533350 0.80 CETP (0.40) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL25118441 0.80 CETP (0.40) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL23533416 0.80 CETP (0.40) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL6685708 0.79 L3MBTL1 (0.58) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL21081916 0.79 L3MBTL1 (0.58) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL14526009 0.79 L3MBTL1 (0.58) L3MBTL1TDP1TSHRALDH1A1CETP
SCHEMBL2886385 0.79 L3MBTL1 (0.58) L3MBTL1TDP1TSHRALDH1A1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230107538-A1 CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF Liminal Biosciences Limited (GB) 2023-04-06 US disclosed
EP-4076649-A1 CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF Liminal Biosciences Limited (GB) 2022-10-26 EP disclosed
CN-114828958-A Cycloalkyl-containing carboxylic acids and use thereof 里米诺生物科学有限公司 2022-07-29 CN disclosed
WO-2021124272-A1 CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF Liminal Biosciences Limited (GB) 2021-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230107538-A1 CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF HCCS, CCL11, BCAT1 L3MBTL1 3163/4885TDP1 4701/4885TSHR 3796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.