Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123871 | 0.88 | NPC1 (0.39) | NPC1RAB9AELANEALDH1A1POLB | |
| SCHEMBL23535396 | 0.85 | ELANE (0.45) | NPC1RAB9AELANEPOLBKMT2A | |
| SCHEMBL28810999 | 0.80 | NPC1 (0.48) | NPC1RAB9AALDH1A1POLBKMT2A | |
| SCHEMBL23533945 | 0.79 | USP30 (0.53) | ALDH1A1POLBKMT2AUSP30KRAS | |
| SCHEMBL29753978 | 0.79 | USP30 (0.53) | ALDH1A1POLBKMT2AUSP30KRAS | |
| SCHEMBL28809790 | 0.78 | RAB9A (0.48) | RAB9AELANEALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29753930 | 0.78 | RAB9A (0.48) | RAB9AELANEALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29754066 | 0.78 | ELANE (0.52) | ELANEKRAS | |
| SCHEMBL4300088 | 0.78 | ELANE (0.55) | ELANEKRAS | |
| SCHEMBL18555671 | 0.78 | ELANE (0.52) | ELANEKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |
| WO-2021125802-A1 | NOVEL INDAZOLE DERIVATIVE, AND USE THEREOF | 한국화학연구원 | 2021-06-24 | — | — | WO | disclosed |