Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29753930 | 1.00 | RAB9A (0.48) | RAB9AALDH1A1ELANENPSR1HPGD | |
| SCHEMBL31123865 | 0.88 | RAB9A (0.40) | RAB9AALDH1A1ELANENPSR1HPGD | |
| SCHEMBL23535396 | 0.84 | ELANE (0.45) | RAB9AELANELMNATHRBTP53 | |
| SCHEMBL23534379 | 0.78 | NPC1 (0.48) | RAB9AALDH1A1ELANESMN1; SMN2LMNA | |
| SCHEMBL23533867 | 0.78 | ABHD6 (0.43) | RAB9AELANEESR2NR1H2 | |
| SCHEMBL29753952 | 0.78 | ABHD6 (0.43) | RAB9AELANEESR2NR1H2 | |
| SCHEMBL4300088 | 0.77 | ELANE (0.55) | ELANE | |
| SCHEMBL18555671 | 0.77 | ELANE (0.52) | ELANE | |
| SCHEMBL29754066 | 0.77 | ELANE (0.52) | ELANE | |
| SCHEMBL18511974 | 0.75 | ELANE (0.65) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |