Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20603150 | 0.82 | SNCA (0.53) | APPSNCACNR1CNR2ALDH1A1 | |
| SCHEMBL12252047 | 0.81 | APP (0.65) | APPSNCACNR1CNR2ALDH1A1 | |
| SCHEMBL24164716 | 0.81 | SNCA (0.57) | APPSNCACNR1CNR2ALDH1A1 | |
| SCHEMBL28377102 | 0.81 | APP (0.57) | APPSNCACNR1CNR2ALDH1A1 | |
| SCHEMBL20603144 | 0.81 | APP (0.57) | APPSNCACNR1CNR2ALDH1A1 | |
| SCHEMBL4358001 | 0.80 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL30379870 | 0.80 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL6706747 | 0.80 | ALDH1A1 (0.64) | APPSNCACNR1CNR2ALDH1A1 | |
| SCHEMBL30426769 | 0.80 | GPBAR1 (0.36) | ALDH1A1SMN1; SMN2LMNATDP1HTT | |
| SCHEMBL30426945 | 0.80 | APP (0.53) | APPSNCAALDH1A1LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172158-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | The Regents of the University of California (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-06 | — | — | US | disclosed |
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-06 | — | — | US | disclosed |
| EP-4077327-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | The Regents of the University of California (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115052876-A | Synthesis of hair growth promoting compounds | 加利福尼亚大学董事会 | 2022-09-13 | — | — | CN | disclosed |
| WO-2021127482-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENT OF THE UNIVERSITY OFCALIFORNIA (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021127482-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | THE REGENT OF THE UNIVERSITY OFCALIFORNIA (US) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230103693-A1 | SYNTHESIS OF COMPOUNDS TO PROMOTE HAIR GROWTH | MKI67, CYP17A1, CYP21A2 | APP 3695/4885SNCA 4834/4885CNR1 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.