Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | CNR1 | P21554 | 4/20 | 0.61 |
| ▸ | CNR2 | P34972 | 4/20 | 0.61 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | SNCA | P37840 | 3/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252047 | 0.88 | APP (0.65) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL23535636 | 0.80 | APP (0.46) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL16750287 | 0.79 | CNR2 (0.48) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL16586481 | 0.79 | ENPP2 (0.60) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL21042783 | 0.79 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL24164296 | 0.79 | APP (0.64) | ALDH1A1CNR1CNR2APPSNCA | |
| SCHEMBL24163776 | 0.78 | APP (0.60) | ALDH1A1CNR1CNR2APPSNCA | |
| SCHEMBL5557953 | 0.78 | PDE4A (0.62) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 | |
| SCHEMBL8690446 | 0.78 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTCNR2APP | |
| SCHEMBL24163770 | 0.77 | SNCA (0.62) | ALDH1A1SMN1; SMN2HTTCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | YANG JI CHEMICAL COMPANY LTD (KR) | 2004-04-08 | — | — | US | disclosed |
| CN-1473160-A | Indole derivatives as medicinal compositions for antifungal and/or antiparasitic agents | 杨池化学有限公司 | 2004-02-04 | — | — | CN | disclosed |
| EP-1322638-A1 | ANTIFUNGAL AND/OR ANTIPARASITIC PHARMACEUTICAL COMPOSITION AND NOVEL INDOLE DERIVATIVES AS ACTIVE PRINCIPLE OF SUCH A COMPOSITION | Yang Ji Chemical Company Ltd. (KR) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024685-A1 | INDOLE DERIVATIVES AND THEIR USE AS ANTIFUNGAL AND/OR ANTIPARASITIC AGENTS | YANG JI CHEMICAL COMPANY LTD. (KR) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067998-A1 | Antifungal and/or antiparasitic pharmaceutical composition and novel indole derivatives as active principle of such a composition | IDO1, IDO2, TPH1 | ALDH1A1 3031/4885SMN1; SMN2 4643/4885HTT 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.