Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201850 | 0.81 | APP (0.38) | GPBAR1ADRB2FPR1GPR183APLNR | |
| SCHEMBL30426742 | 0.81 | APP (0.38) | GPBAR1ADRB2FPR1GPR183APLNR | |
| SCHEMBL23535636 | 0.80 | APP (0.46) | SMN1; SMN2HTTALDH1A1LMNATDP1 | |
| SCHEMBL30426708 | 0.78 | APP (0.45) | ALDH1A1LMNA | |
| SCHEMBL24165405 | 0.78 | APP (0.45) | ALDH1A1LMNA | |
| SCHEMBL30426923 | 0.77 | APP (0.36) | SMN1; SMN2HTTALDH1A1LMNAKDM4E | |
| SCHEMBL22201852 | 0.77 | MIF (0.41) | SMN1; SMN2ALDH1A1LMNAKDM4ETDP1 | |
| SCHEMBL30426404 | 0.77 | MIF (0.41) | SMN1; SMN2ALDH1A1LMNAKDM4ETDP1 | |
| SCHEMBL20603154 | 0.72 | APP (0.39) | ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL28380649 | 0.72 | APP (0.39) | ALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172158-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | The Regents of the University of California (US) | 2023-05-03 | — | — | EP | disclosed |