Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536071 | 0.83 | USP2 (0.45) | TSHRUSP2TACR1 | |
| SCHEMBL23536214 | 0.79 | CNR2 (0.36) | — | |
| SCHEMBL3324938 | 0.77 | CYP3A4 (0.37) | CYP2D6TSHRUSP2ALDH1A1CYP3A4 | |
| SCHEMBL17815708 | 0.75 | SCN9A (0.32) | SCN9A | |
| SCHEMBL5566107 | 0.75 | CYP2D6 (0.36) | CYP2D6TSHRUSP2ALDH1A1CYP3A4 | |
| SCHEMBL24615840 | 0.74 | SMN1; SMN2 (0.41) | USP2CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1242770 | 0.73 | — | — | |
| SCHEMBL18497005 | 0.72 | ALDH1A1 (0.36) | CYP2D6TSHRUSP2ALDH1A1CYP3A4 | |
| SCHEMBL16449040 | 0.72 | SCN9A (0.35) | SCN9A | |
| SCHEMBL17009549 | 0.71 | CYP2D6 (0.36) | CYP2D6TSHRUSP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |