SCHEMBL23536214

SCHEMBL23536214

O=C(O)N1CCC(CO)(C(F)(F)F)CC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.36
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23536294 0.79 CYP2D6 (0.34)
SCHEMBL1242770 0.79
SCHEMBL23536114 0.76 USP2 (0.46)
SCHEMBL23253117 0.75 CYP46A1 (0.33)
SCHEMBL3869090 0.74 VNN1 (0.38) CNR2
SCHEMBL619913 0.74 VNN1 (0.36) NPC1
SCHEMBL17146 0.73
SCHEMBL2209078 0.73 ALDH1A1 (0.37) NPC1
SCHEMBL19717769 0.72 DGAT1 (0.32)
SCHEMBL24809836 0.71 USP2 (0.41) CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021127337-A1 TRPML MODULATORS CASMA THERAPEUTICS, INC. (US) 2021-06-24 WO disclosed